Basic statistical analysis in genetic case-control studies
نویسندگان
چکیده
منابع مشابه
Case-control studies: basic concepts.
The purpose of this article is to present in elementary mathematical and statistical terms a simple way to quickly and effectively teach and understand case-control studies, as they are commonly done in dynamic populations-without using the rare disease assumption. Our focus is on case-control studies of disease incidence ('incident case-control studies'); we will not consider the situation of ...
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Case-control association studies use genetic markers as putative etiologic risk factors. The approach is controversial and has tended to produce associations in neuropsychiatry that do not stand the test of time. We studied the processes that can bias the outcomes away from a true representation of the relationship between a genetic marker and a neuropsychiatric disorder. If conducted with care...
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Make more knowledge even in less time every day. You may not always spend your time and money to go abroad and get the experience and knowledge by yourself. Reading is a good alternative to do in getting this desirable knowledge and experience. You may gain many things from experiencing directly, but of course it will spend much money. So here, by reading statistical methods in cancer research ...
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BACKGROUND Case-control studies are a common and efficient means of studying rare diseases or illnesses with long latency periods. Matching of cases and controls is frequently employed to control the effects of known potential confounding variables. The analysis of matched data requires specific statistical methods. METHODS The objective of this study was to determine the proportion of publis...
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ژورنال
عنوان ژورنال: Nature Protocols
سال: 2011
ISSN: 1754-2189,1750-2799
DOI: 10.1038/nprot.2010.182